- accession:NM_011511
- 基因别名:Sur2; SUR2A; SUR2B; AI414027; AI449286
- 基因描述:Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (Abcc9), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:4641
- 翻译后氨基酸长度:1546
- TranscriptVariant:This variant (1) differs in the 3' UTR and coding region compared to variant 2. The resulting isoform (a, also known as SUR2B) has a distinct C-terminus compared to isoform b.
- 基因简介:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The human protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. Alternative splicing of this gene results in four known transcript variants and several other variants that have not yet been fully described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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