资料下载
- 靶点-Target: JAK1
- MW(Observed): 130kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:200-1000;ICC 1:200;IF 1:50-200
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human Jak1 protein fragments expressed in E.coli.
- 特异性: This antibody detects endogenous levels of Jak1 and does not cross-react with related proteins.
- 基因名称: jak1
- Organism-1: Human
- 基因ID-1: 3716
- SwissProt-1: P23458
- Organism-2: Mouse
- SwissProt-2: P52332
- 背景: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
- 细胞定位: Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.