• 靶点-Target： COX IV
• MW(Calculated)： 20kD
• MW(Observed)： 17kD
• 宿主物种-Host Species： Mouse
• 同种型-Isotype： IgG2b，kappa
• 修饰-Modification： Unmodified
• 推荐稀释比： IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
• 组成： PBS， 50% glycerol， 0.05% Proclin 300， 0.05%BSA
• 纯化工艺： The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 克隆号： PTR1399
• 免疫原： AA range: 100-200
• 特异性： This antibody detects endogenous levels of COX IV protein.
• 基因名称： COX4I1
• 蛋白名称： Cytochrome c oxidase subunit 4 isoform 1， mitochondrial
• Organism-1： Human
• 基因ID-1： 1327
• SwissProt-1： P13073
• Organism-2： Mouse
• 基因ID-2： 12857
• SwissProt-2： P19783
• Organism-3： Rat
• 基因ID-3： 29445
• SwissProt-3： P10888
• 背景： Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation， and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
• 细胞定位： Mitochondrion inner membrane

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