• 靶点-Target： AMACR
• MW(Observed)： 42kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:1000;IHC 1:200;IF 1:200
• 组成： PBS， pH 7.4， containing 0.5%BSA， 0.02% sodium azide as Preservative and 50% Glycerol.
• 纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 克隆号： 4A12
• 免疫原： Synthetic Peptide of AMACR
• 特异性： The antibody detects endogenous AMCAR/P504S proteins.
• 基因名称： AMACR
• 蛋白名称： Alpha-methylacyl-CoA racemase
• Organism-1： Human
• 基因ID-1： 23600
• SwissProt-1： Q9UHK6
• Organism-2： Mouse
• 基因ID-2： 17117
• SwissProt-2： O09174
• Organism-3： Rat
• SwissProt-3： P70473
• 背景： This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy， pigmentary retinopathy， and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq， Mar 2011]，
• 细胞定位： Peroxisome . Mitochondrion .

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