- accession:NM_173843
- 基因别名:IL1RN
- 基因描述:Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mRNA.
- 载体: 现货载体
- CDS区长度:432
- 翻译后氨基酸长度:143
- TranscriptVariant:This variant (4) contains a distinct internal exon compared to variant 2. This results in translation from a downstream start codon, and an isoform (4) that has a shorter N-terminus, as compared to the longest isoform (2).
- 基因简介:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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