- accession:NM_022173
- 基因别名:TIA1
- 基因描述:Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein (TIA1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1161
- 翻译后氨基酸长度:386
- TranscriptVariant:This variant (2) includes exon 5, which is missing in transcript variant 1, resulting in the longer isoform (2).
- 基因简介:The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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