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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 F8 (NM_000132) cDNA克隆
人 F8 (NM_000132) cDNA克隆
人 F8 (NM_000132) cDNA克隆
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    • accession：NM_000132
    • 基因别名：F8
    • 基因描述：Homo sapiens coagulation factor VIII, procoagulant component (F8), transcript variant 1, mRNA.
    • 载体：现货载体
    • CDS区长度：7056
    • 翻译后氨基酸长度：2351
    • TranscriptVariant：This variant (1) consists of 26 exons and encodes the full-length isoform (a)
    • 基因简介：This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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