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- accession：NM_001080123
- 基因别名：PRNP
- 基因描述：Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：762
- 翻译后氨基酸长度：253
- TranscriptVariant：This variant (5) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein.
- 基因简介：The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
