- accession:NM_133274
- 基因别名:FCAR
- 基因描述:Homo sapiens Fc fragment of IgA, receptor for (FCAR), transcript variant 6, mRNA.
- 载体:现货载体
- CDS区长度:630
- 翻译后氨基酸长度:209
- TranscriptVariant:This variant (6), also called deltaS2S374EC2, lacks exon S2 and the last 74 nt of exon EC2 as compared to variant 1. As a result, variant 6 encodes isoform f, which has the same N-terminus but different C-terminus and which lacks an internal 12 aa region as compared to isoform a encoded by variant 1.
- 基因简介:This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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