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- accession：NM_022550
- 基因别名：XRCC4
- 基因描述：Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1005
- 翻译后氨基酸长度：334
- TranscriptVariant：This variant (3) is the longest transcript; it has an additional segment in the 5' UTR and lacks a small segment in the 3' coding region, as compared to variant 2. Both variants 1 and 3 encode the same isoform (1), which is shorter than isoform 2.
- 基因简介：The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
