- accession:NM_001145713
- 基因别名:SAE1
- 基因描述:Homo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:900
- 翻译后氨基酸长度:299
- TranscriptVariant:This variant (2) lacks two alternate exons, compared to variant 1, which causes a frameshift. The resulting protein (isoform b) has a distinct C-terminus and is shorter than isoform a.
- 基因简介:Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列