- accession:NM_178580
- 基因别名:HM13
- 基因描述:Homo sapiens histocompatibility (minor) 13 (HM13), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1185
- 翻译后氨基酸长度:394
- TranscriptVariant:This variant (2) contains an alternate exon compared to variant 1, that causes a frameshift. The resulting isoform (2) is longer and has a distinct C-terminus compared to isoform 1.
- 基因简介:The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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