- accession:NM_006096
- 基因别名:NDRG1
- 基因描述:Homo sapiens N-myc downstream regulated 1 (NDRG1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1185
- 翻译后氨基酸长度:394
- TranscriptVariant:This variant (2) uses an alternate splice site in the 5' UTR. Variants 1 and 2 encode the same isoform (1).
- 基因简介:This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列