- accession:NM_203389
- 基因别名:RNH1
- 基因描述:Homo sapiens ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 8, mRNA.
- 载体:现货载体
- CDS区长度:1386
- 翻译后氨基酸长度:461
- TranscriptVariant:This variant (8) has multiple differences in its 5' UTR, compared to variant 1. All eight variants of this gene encode the same protein.
- 基因简介:Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]
- 规格:10ul 质粒
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