- accession:NM_001166694
- 基因别名:CHRNA3
- 基因描述:Homo sapiens cholinergic receptor, nicotinic, alpha 3 (neuronal) (CHRNA3), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1470
- 翻译后氨基酸长度:489
- TranscriptVariant:This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1.
- 基因简介:This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
- 规格:10ul 质粒
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