- accession:NM_080796
- 基因别名:DIDO1
- 基因描述:Homo sapiens death inducer-obliterator 1 (DIDO1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1689
- 翻译后氨基酸长度:562
- TranscriptVariant:This variant (2) contains a different 5' UTR segment and lacks most of the 3' coding region, compared to variant 4. The resulting protein (isoform a) has a shorter and distinct C-terminus when it is compared to isoform c. Variants 1 and 2 encode the same protein (isoform a).
- 基因简介:Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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