服务热线：
- 商品货号：G102328
- accession：NM_001243759
- 基因别名：USP2
- 基因描述：Homo sapiens ubiquitin specific peptidase 2 (USP2), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1089
- 翻译后氨基酸长度：362
- TranscriptVariant：This variant (3) lacks an internal exon in the 5' region, compared to variant 1. The resulting isoform (c) has a shorter and different N-terminus compared to isoform a.
- 基因简介：This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
服务时间：24小时在线客服
客服热线：400-000-7085
丰晖生物
中国优质生物资源平台
在线客服