- accession:NM_001244973
- 基因别名:NRP1
- 基因描述:Homo sapiens neuropilin 1 (NRP1), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:2751
- 翻译后氨基酸长度:916
- TranscriptVariant:This variant (5) uses a different splice site in the coding region, compared to variant 1. The resulting protein (isoform e) is shorter when it is compared to isoform a.
- 基因简介:This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
- 规格:10ul 质粒
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