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- accession：NM_001137559
- 基因别名：ANAPC5
- 基因描述：Homo sapiens anaphase promoting complex subunit 5 (ANAPC5), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1932
- 翻译后氨基酸长度：643
- TranscriptVariant：This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the internal coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in a shorter isoform (b) compared to isoform a.
- 基因简介：This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
