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- accession：NM_001258274
- 基因别名：MLH1
- 基因描述：Homo sapiens mutL homolog 1 (MLH1), transcript variant 7, mRNA.
- 载体：现货载体
- CDS区长度：1548
- 翻译后氨基酸长度：515
- TranscriptVariant：This variant (7) differs in the 5' UTR and contains an alternate exon compared to variant 1, that causes a frameshift. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Variants 3, 4, 6, and 7 all encode the same isoform (3).
- 基因简介：This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
