- accession:NM_001282690
- 基因别名:SECISBP2
- 基因描述:Homo sapiens SECIS binding protein 2 (SECISBP2), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:2361
- 翻译后氨基酸长度:786
- TranscriptVariant:This variant (4) uses an alternate terminal exon which results in the use of a downstream start codon compared to variant 1. The encoded isoform (4) has a shorter N-terminus compared to isoform 1
- 基因简介:The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- 规格:10ul 质粒
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