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- accession：NM_080918
- 基因别名：DGUOK
- 基因描述：Homo sapiens deoxyguanosine kinase (DGUOK), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：570
- 翻译后氨基酸长度：189
- TranscriptVariant：This variant (2) lacks an alternate in-frame exon in the coding region, as compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
- 基因简介：In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
