• accession：NM_020130
• 基因别名：C8orf4
• 基因描述：Homo sapiens chromosome 8 open reading frame 4 (C8orf4), mRNA.
• 载体：现货载体
• CDS区长度：321
• 翻译后氨基酸长度：106
• 基因简介：This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAAAGCAAAGCGAAGCCACCAAGCCATCATCATGTCCACGTCGCTACGAGTCAGCCCATCCATCCATG
GCTACCACTTCGACACAGCCTCTCGTAAGAAAGCCGTGGGCAACATCTTTGAAAACACAGACCAAGAATC
ACTAGAAAGGCTCTTCAGAAACTCTGGAGACAAGAAAGCAGAGGAGAGAGCCAAGATCATTTTTGCCATA
GATCAAGATGTGGAGGAGAAAACGCGTGCCCTGATGGCCTTGAAGAAGAGGACAAAAGACAAGCTTTTCC
AGTTTCTGAAACTGCGGAAATATTCCATCAAAGTTCACTGA

翻译后氨基酸参数序列： 点击查看序列

ATGAAAGCAAAGCGAAGCCACCAAGCCATCATCATGTCCACGTCGCTACGAGTCAGCCCATCCATCCATG
GCTACCACTTCGACACAGCCTCTCGTAAGAAAGCCGTGGGCAACATCTTTGAAAACACAGACCAAGAATC
ACTAGAAAGGCTCTTCAGAAACTCTGGAGACAAGAAAGCAGAGGAGAGAGCCAAGATCATTTTTGCCATA
GATCAAGATGTGGAGGAGAAAACGCGTGCCCTGATGGCCTTGAAGAAGAGGACAAAAGACAAGCTTTTCC
AGTTTCTGAAACTGCGGAAATATTCCATCAAAGTTCACTGA