- accession:NM_001243798
- 基因别名:TSC22D1
- 基因描述:Homo sapiens TSC22 domain family, member 1 (TSC22D1), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:261
- 翻译后氨基酸长度:86
- TranscriptVariant:This variant (4) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 3 and 4 encode the same isoform (3), which has a significantly shorter N-terminus compared to isoform 1.
- 基因简介:This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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