- accession:NM_002371
- 基因别名:MAL
- 基因描述:Homo sapiens mal, T-cell differentiation protein (MAL), transcript variant a, mRNA.
- 载体:现货载体
- CDS区长度:462
- 翻译后氨基酸长度:153
- TranscriptVariant:This variant (a) includes both alternatively spliced exons 2 and 3, resulting in the longest isoform (a).
- 基因简介:The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
- 规格:10ul 质粒
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