- accession:NM_001278369
- 基因别名:RHOH
- 基因描述:Homo sapiens ras homolog family member H (RHOH), transcript variant 12, mRNA.
- 载体:现货载体
- CDS区长度:576
- 翻译后氨基酸长度:191
- TranscriptVariant:This variant (12) contains an alternate 5' exon and lacks two exons in the 5' UTR, compared to variant 1. Variants 1 through 12 encode the same protein.
- 基因简介:The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]
- 规格:10ul 质粒
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