- accession:NM_022645
- 基因别名:CSH2
- 基因描述:Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:369
- 翻译后氨基酸长度:122
- TranscriptVariant:This variant (3) lacks exons 3 and 4, and encodes an isoform (3) that has an internal deletion relative to isoform 1, but retains the signal sequence, unlike the other exon skipping isoform (4).
- 基因简介:The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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