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- accession：NM_138578
- 基因别名：BCL2L1
- 基因描述：Homo sapiens BCL2-like 1 (BCL2L1), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：702
- 翻译后氨基酸长度：233
- TranscriptVariant：This variant (1) is also known as bcl-xL. It encodes a longer isoform (1).
- 基因简介：The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
