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- accession：NM_000367
- 基因别名：TPMT
- 基因描述：Homo sapiens thiopurine S-methyltransferase (TPMT), mRNA.
- 载体：现货载体
- CDS区长度：738
- 翻译后氨基酸长度：245
- 基因简介：This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
