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- accession：NM_001282520
- 基因别名：BCL2L12
- 基因描述：Homo sapiens BCL2-like 12 (proline rich) (BCL2L12), transcript variant 10, mRNA.
- 载体：现货载体
- CDS区长度：669
- 翻译后氨基酸长度：222
- TranscriptVariant：This variant (10) lacks two alternate exons in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (6) is shorter and has a distinct C-terminus, compared to isoform 1.
- 基因简介：This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
