• accession：NM_016237
• 基因别名：ANAPC5
• 基因描述：Homo sapiens anaphase promoting complex subunit 5 (ANAPC5), transcript variant 1, mRNA.
• 载体： 现货载体
• CDS区长度：2268
• 翻译后氨基酸长度：755
• TranscriptVariant：This variant (1) represents the longer transcript and encodes the longer isoform (a).
• 基因简介：This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGCCAGCGTCCACGAGAGCCTCTACTTCAATCCCATGATGACCAATGGGGTTGTGCACGCCAATGTGTTCGGCATCAAGGACTGGGTGACGCCGTACAAGATCGCGGTGCTGGTGCTGCTGAACGAGATGAGCCGCACAGGCGAGGGCGCCGTCAGCCTCATGGAGCGGCGGAGGCTCAACCAGCTGCTCCTGCCCCTGCTGCAGGGCCCAGATATTACACTGTCAAAACTTTACAAGTTAATTGAAGAGTCTTGTCCACAGCTGGCAAATTCAGTGCAGATCAGAATCAAACTGATGGCTGAAGGCGAGTTGAAGGATATGGAACAGTTTTTTGATGACCTTTCAGATTCTTTCTCTGGAACTGAACCAGAGGTTCACAAAACAAGTGTAGTAGGTTTGTTTCTGCGTCACATGATCTTGGCCTACAGTAAGCTTTCTTTCAGCCAAGTGTTTAAACTGTACACTGCCCTTCAGCAGTACTTCCAGAATGGTGAGAAAAAGACAGTGGAGGATGCTGATATGGAACTGACCAGTAGAGATGAGGGTGAAAGAAAAATGGAAAAAGAAGAACTTGATGTATCTGTAAGAGAAGAGGAGGTATCTTGCAGTGGGCCTCTGTCCCAAAAACAAGCAGAATTTTTTCTTTCTCAACAGGCTTCTTTGCTAAAGAATGATGAGACTAAGGCCCTCACTCCAGCTTCCTTGCAGAAGGAATTAAACAATTTGTTGAAATTTAATCCTGATTTTGCTGAAGCGCATTATCTCAGCTACTTAAACAACCTCCGTGTCCAAGATGTTTTCAGTTCAACACACAGTCTCCTCCATTATTTTGATCGTCTGATTCTTACCGGAGCCGAAAGCAAAAGTAATGGGGAAGAGGGCTATGGCCGGAGCTTGAGATACGCCGCTCTGAATCTTGCCGCCCTGCACTGCCGCTTCGGTCACTATCAACAGGCAGAGCTCGCCCTGCAGGAGGCAATTAGGATTGCCCAGGAGTCCAACGATCACGTGTGTCTCCAGCACTGTTTGAGCTGGCTTTATGTGCTGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTACATTTTGGGTTACCGTACCTCGCCTCCCTGGGAATACAGTCCCTTGTTCAACAGAGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACTCCGACCTCCTGCACTGGAAACACAGCCTGTCAGAGCTCATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCAGCACCATGGCACTGCAACAGGCCCAGATGTTGCTGAGCATGAACAGCCTGGAGGCGGTGAATGCGGGCGTGCAGCAGAACAACACAGAGTCCTTTGCTGTCGCACTCTGCCACCTCGCAGAGCTACACGCGGAGCAGGGCTGTTTTGCTGCAGCTTCTGAAGTGTTAAAGCACTTGAAGGAACGATTTCCGCCTAATAGTCAGCACGCCCAGTTATGGATGCTATGTGATCAAAAAATACAGTTTGACAGAGCAATGAATGATGGCAAATATCATTTGGCTGATTCACTTGTTACAGGAATCACAGCTCTCAATAGCATAGAGGGTGTTTATAGGAAAGCGGTTGTATTACAAGCTCAGAACCAAATGTCAGAGGCACATAAGCTTTTACAAAAATTGTTGGTTCATTGTCAGAAACTGAAGAACACAGAAATGGTGATCAGTGTCCTACTGTCCGTGGCAGAGCTGTACTGGCGATCTTCCTCCCCTACCATCGCGCTGCCCATGCTCCTGCAGGCTCTGGCCCTCTCCAAGGAGTACCGGTTACAGTACTTGGCCTCTGAAACAGTGCTGAACTTGGCTTTTGCGCAGCTCATTCTTGGAATCCCAGAACAGGCCTTAAGTCTTCTCCACATGGCCATCGAGCCCATCTTGGCTGACGGGGCTATCCTGGACAAAGGTCGTGCCATGTTCTTAGTGGCCAAGTGCCAGGTGGCTTCAGCAGCTTCCTACGATCAGCCGAAGAAAGCAGAAGCTCTGGAGGCTGCCATCGAGAACCTCAATGAAGCCAAGAACTATTTTGCAAAGGTTGACTGCAAAGAGCGCATCAGGGACGTCGTTTACTTCCAGGCCAGACTCTACCATACCCTGGGGAAGACCCAGGAGAGGAACCGGTGTGCGATGCTCTTCCGGCAGCTGCATCAGGAGCTGCCCTCTCATGGGGTACCCTTGATAAACCATCTCTAG

翻译后氨基酸参数序列： 点击查看序列

ATGGCCAGCGTCCACGAGAGCCTCTACTTCAATCCCATGATGACCAATGGGGTTGTGCACGCCAATGTGTTCGGCATCAAGGACTGGGTGACGCCGTACAAGATCGCGGTGCTGGTGCTGCTGAACGAGATGAGCCGCACAGGCGAGGGCGCCGTCAGCCTCATGGAGCGGCGGAGGCTCAACCAGCTGCTCCTGCCCCTGCTGCAGGGCCCAGATATTACACTGTCAAAACTTTACAAGTTAATTGAAGAGTCTTGTCCACAGCTGGCAAATTCAGTGCAGATCAGAATCAAACTGATGGCTGAAGGCGAGTTGAAGGATATGGAACAGTTTTTTGATGACCTTTCAGATTCTTTCTCTGGAACTGAACCAGAGGTTCACAAAACAAGTGTAGTAGGTTTGTTTCTGCGTCACATGATCTTGGCCTACAGTAAGCTTTCTTTCAGCCAAGTGTTTAAACTGTACACTGCCCTTCAGCAGTACTTCCAGAATGGTGAGAAAAAGACAGTGGAGGATGCTGATATGGAACTGACCAGTAGAGATGAGGGTGAAAGAAAAATGGAAAAAGAAGAACTTGATGTATCTGTAAGAGAAGAGGAGGTATCTTGCAGTGGGCCTCTGTCCCAAAAACAAGCAGAATTTTTTCTTTCTCAACAGGCTTCTTTGCTAAAGAATGATGAGACTAAGGCCCTCACTCCAGCTTCCTTGCAGAAGGAATTAAACAATTTGTTGAAATTTAATCCTGATTTTGCTGAAGCGCATTATCTCAGCTACTTAAACAACCTCCGTGTCCAAGATGTTTTCAGTTCAACACACAGTCTCCTCCATTATTTTGATCGTCTGATTCTTACCGGAGCCGAAAGCAAAAGTAATGGGGAAGAGGGCTATGGCCGGAGCTTGAGATACGCCGCTCTGAATCTTGCCGCCCTGCACTGCCGCTTCGGTCACTATCAACAGGCAGAGCTCGCCCTGCAGGAGGCAATTAGGATTGCCCAGGAGTCCAACGATCACGTGTGTCTCCAGCACTGTTTGAGCTGGCTTTATGTGCTGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTACATTTTGGGTTACCGTACCTCGCCTCCCTGGGAATACAGTCCCTTGTTCAACAGAGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACTCCGACCTCCTGCACTGGAAACACAGCCTGTCAGAGCTCATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCAGCACCATGGCACTGCAACAGGCCCAGATGTTGCTGAGCATGAACAGCCTGGAGGCGGTGAATGCGGGCGTGCAGCAGAACAACACAGAGTCCTTTGCTGTCGCACTCTGCCACCTCGCAGAGCTACACGCGGAGCAGGGCTGTTTTGCTGCAGCTTCTGAAGTGTTAAAGCACTTGAAGGAACGATTTCCGCCTAATAGTCAGCACGCCCAGTTATGGATGCTATGTGATCAAAAAATACAGTTTGACAGAGCAATGAATGATGGCAAATATCATTTGGCTGATTCACTTGTTACAGGAATCACAGCTCTCAATAGCATAGAGGGTGTTTATAGGAAAGCGGTTGTATTACAAGCTCAGAACCAAATGTCAGAGGCACATAAGCTTTTACAAAAATTGTTGGTTCATTGTCAGAAACTGAAGAACACAGAAATGGTGATCAGTGTCCTACTGTCCGTGGCAGAGCTGTACTGGCGATCTTCCTCCCCTACCATCGCGCTGCCCATGCTCCTGCAGGCTCTGGCCCTCTCCAAGGAGTACCGGTTACAGTACTTGGCCTCTGAAACAGTGCTGAACTTGGCTTTTGCGCAGCTCATTCTTGGAATCCCAGAACAGGCCTTAAGTCTTCTCCACATGGCCATCGAGCCCATCTTGGCTGACGGGGCTATCCTGGACAAAGGTCGTGCCATGTTCTTAGTGGCCAAGTGCCAGGTGGCTTCAGCAGCTTCCTACGATCAGCCGAAGAAAGCAGAAGCTCTGGAGGCTGCCATCGAGAACCTCAATGAAGCCAAGAACTATTTTGCAAAGGTTGACTGCAAAGAGCGCATCAGGGACGTCGTTTACTTCCAGGCCAGACTCTACCATACCCTGGGGAAGACCCAGGAGAGGAACCGGTGTGCGATGCTCTTCCGGCAGCTGCATCAGGAGCTGCCCTCTCATGGGGTACCCTTGATAAACCATCTCTAG