- accession:NM_006895
- 基因别名:HNMT
- 基因描述:Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:879
- 翻译后氨基酸长度:292
- TranscriptVariant:This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
- 基因简介:In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列