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- accession：NM_001282575
- 基因别名：UBE2V1
- 基因描述：Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), transcript variant 12, mRNA.
- 载体：现货载体
- CDS区长度：276
- 翻译后氨基酸长度：91
- TranscriptVariant：This variant (12) uses an alternate 5' exon structure, and thus differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at an alternate AUG and result in an isoform (h) with a shorter and distinct N-terminus, compared to isoform a. Variants 12, 15, and 16 encode the same isoform (h).
- 基因简介：Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
