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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 NIPBL (NM_015384) cDNA克隆
人 NIPBL (NM_015384) cDNA克隆
人 NIPBL (NM_015384) cDNA克隆
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    • accession：NM_015384
    • 基因别名：NIPBL
    • 基因描述：Homo sapiens Nipped-B homolog (Drosophila) (NIPBL), transcript variant B, mRNA.
    • 载体：现货载体
    • CDS区长度：8094
    • 翻译后氨基酸长度：2697
    • TranscriptVariant：This variant (B) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (B) with a shorter, distinct C-terminus, compared to isoform A.
    • 基因简介：This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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