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- accession：NM_080913
- 基因别名：ASGR2
- 基因描述：Homo sapiens asialoglycoprotein receptor 2 (ASGR2), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：864
- 翻译后氨基酸长度：287
- TranscriptVariant：This variant (2), also known as H2c and L-H2, differs in the 5' UTR and uses two alternate splice sites in the 5' coding region, but maintains the reading frame, compared to variant H2'. The encoded isoform (b) is shorter than isoform a.
- 基因简介：This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
