• accession：NM_017610
• 基因别名：RNF111
• 基因描述：Homo sapiens ring finger protein 111 (RNF111), transcript variant 2, mRNA.
• 载体： 现货载体
• CDS区长度：2961
• 翻译后氨基酸长度：986
• TranscriptVariant：This variant (2) lacks an in-frame segment in the 3' coding region, compared to variant 1, which results in a shorter protein (isoform 2), compared to isoform 1.
• 基因简介：The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGCAGGCATTGCCAGTGGACCTGAGCAACAGTGGTATCAGAAGTCATGGAAGTGGCAGTTTTCATGGAGCATCTGCATTTGACCCCTGCTGCCCTGTTTCTTCCTCCCGAGCTGCAATCTTTGGCCATCAGGCCGCTGCTGCTGCCCCAAGTCAACCTTTATCATCAATAGATGGCTATGGATCAAGCATGGTTGCGCAGCCCCAGCCCCAGCCCCCTCCACAGCCCTCTCTCTCATCATGTCGACATTACATGCCACCCCCTTATGCCTCTTTGACAAGGCCACTTCATCATCAAGCTTCTGCCTGCCCGCATTCTCATGGAAACCCCCCTCCTCAGACTCAGCCTCCGCCTCAAGTGGATTATGTTATTCCTCATCCTGTACATGCTTTCCATTCTCAAATATCTTCTCATGCAACATCTCATCCTGTGGCACCCCCACCACCAACTCACTTAGCCAGTACAGCTGCACCAATCCCTCAGCATCTTCCTCCTACACACCAGCCAATTTCGCACCATATTCCAGCCACAGCACCTCCAGCACAGAGACTGCATCCTCATGAAGTGATGCAGAGGATGGAAGTTCAAAGGAGGAGGATGATGCAGCATCCAACGCGGGCACATGAACGCCCCCCACCCCATCCACATAGGATGCACCCAAACTATGGTCATGGGCATCATATTCATGTGCCTCAGACTATGTCCTCACATCCTCGACAGGCTCCAGAGAGGTCTGCCTGGGAACTGGGAATTGAAGCTGGAGTGACTGCAGCTACTTATACACCTGGTGCATTGCATCCTCACTTGGCCCATTATCACGCACCTCCTCGACTTCATCACTTACAATTAGGAGCTCTTCCTTTAATGGTTCCTGATATGGCAGGCTATCCTCACATCCGTTACATTTCATCAGGATTGGATGGAACATCATTCAGAGGTCCTTTCAGGGGCAATTTTGAGGAACTGATTCATTTGGAAGAAAGATTAGGCAATGTCAATCGTGGAGCATCCCAGGGGACAATTGAAAGATGTACATATCCACATAAATACAAAAAGAGGAAACTGCACTGCAAACAAGATGGGGAAGAAGGGACTGAGGAAGACACAGAGGAAAAATGTACTATCTGTTTGTCTATTTTAGAGGAAGGTGAAGATGTGAGACGTCTTCCATGTATGCACCTTTTCCACCAAGTGTGTGTTGACCAATGGTTGATTACCAATAAGAAGTGCCCCATATGCAGAGTGGACATTGAGGCCCAGCTGCCAAGTGAAAGTTGA

翻译后氨基酸参数序列： 点击查看序列

ATGTCTCAATGGACTCCTGAATATAACGAGCTCTACACCTTAAAAGTGGATATGAAGAGTGAGATTCCTTCTGATGCACCAAAGACACAGGAGAGTCTGAAAGGGATCCTTTTGCATCCAGAGCCCATTGGGGCAGCCAAAAGTTTTCCTGCAGGAGTTGAGATGATTAATAGTAAAGTGGGGAATGAATTCTCTCACCTGTGTGATGATTCTCAAAAGCAAGAGAAGGAAATGAATGGTAACCAGCAAGAACAAGAAAAAAGTCTCGTTGTGAGGAAAAAACGCAAAAGCCAGCAGGCTGGCCCTTCGTATGTGCAGAATTGTGTTAAAGAAAACCAGGGAATATTAGGACTGAGGCAACACCTAGGGACACCAAGTGATGAAGATAATGATTCCTCTTTTAGTGATTGTCTTTCTTCTCCTTCATCTAGTCTGCATTTTGGAGATTCTGATACTGTGACTTCAGATGAGGATAAAGAAGTCTCTGTAAGACATTCCCAGACCATTTTGAATGCTAAAAGTAGAAGCCATAGTGCACGGTCTCATAAGTGGCCTCGGACTGAGACAGAATCTGTATCGGGATTGTTAATGAAAAGACCCTGTTTACATGGCAGTTCGTTACGGAGACTTCCATGCAGAAAGAGATTTGTAAAAAATAATTCCTCACAGAGGACACAGAAACAAAAAGAGAGGATATTAATGCAGAGGAAGAAACGAGAAGTGTTAGCTCGAAGAAAATATGCCTTGCTACCTAGTTCTAGTAGTTCCAGTGAGAATGACCTCAGCAGTGAATCCTCTTCTAGCTCATCAACTGAAGGAGAAGAAGATTTGTTTGTTTCTGCCAGTGAAAACCACCAAAACAATCCAGCTGTTCCCTCAGGAAGTATTGATGAAGATGTTGTGGTGATAGAAGCTTCCTCCACTCCCCAGGTTACTGCCAATGAAGAAATTAATGTTACCTCAACTGACAGTGAAGTGGAGATTGTAACAGTTGGAGAAAGCTATCGGTCTCGTTCAACCCTTGGACACTCCAGATCTCATTGGAGCCAGGGTTCCAGTTCTCATGCAAGTCGGCCACAGGAGCCACGGAACCGCAGTAGGATTTCTACTGTTATACAGCCCTTGAGGCAGAATGCAGCAGAAGTTGTGGACCTTACCGTTGATGAAGATGAACCTACTGTAGTACCAACCACTTCTGCAAGAATGGAATCACAAGCTACTAGCGCTTCCATTAACAATTCAAATCCATCTACCTCTGAGCAGGCCTCTGATACTGCTTCAGCTGTCACCAGTAGCCAACCTTCCACAGTGTCAGAGACTTCAGCTACTCTTACAAGCAATAGTACCACTGGCACTTCTATAGGAGATGACTCAAGGAGAACTACATCTAGTGCTGTAACGGAAACTGGCCCTCCTGCAATGCCAAGGTTACCTTCCTGCTGTCCCCAGCACTCACCATGTGGAGGGTCGTCACAGAACCACCATGCATTAGGACATCCTCATACAAGTTGCTTTCAGCAGCATGGTCACCATTTTCAACATCATCACCACCACCACCATACTCCCCACCCAGCTGTCCCAGTTTCTCCTTCCTTTAGTGATCCTGCTTGCCCTGTGGAAAGACCTCCACAAGTACAAGCACCTTGTGGAGCAAATAGTAGTTCTGGTACCAGCTATCATGAACAGCAGGCATTGCCAGTGGACCTGAGCAACAGTGGTATCAGAAGTCATGGAAGTGGCAGTTTTCATGGAGCATCTGCATTTGACCCCTGCTGCCCTGTTTCTTCCTCCCGAGCTGCAATCTTTGGCCATCAGGCCGCTGCTGCTGCCCCAAGTCAACCTTTATCATCAATAGATGGCTATGGATCAAGCATGGTTGCGCAGCCCCAGCCCCAGCCCCCTCCACAGCCCTCTCTCTCATCATGTCGACATTACATGCCACCCCCTTATGCCTCTTTGACAAGGCCACTTCATCATCAAGCTTCTGCCTGCCCGCATTCTCATGGAAACCCCCCTCCTCAGACTCAGCCTCCGCCTCAAGTGGATTATGTTATTCCTCATCCTGTACATGCTTTCCATTCTCAAATATCTTCTCATGCAACATCTCATCCTGTGGCACCCCCACCACCAACTCACTTAGCCAGTACAGCTGCACCAATCCCTCAGCATCTTCCTCCTACACACCAGCCAATTTCGCACCATATTCCAGCCACAGCACCTCCAGCACAGAGACTGCATCCTCATGAAGTGATGCAGAGGATGGAAGTTCAAAGGAGGAGGATGATGCAGCATCCAACGCGGGCACATGAACGCCCCCCACCCCATCCACATAGGATGCACCCAAACTATGGTCATGGGCATCATATTCATGTGCCTCAGACTATGTCCTCACATCCTCGACAGGCTCCAGAGAGGTCTGCCTGGGAACTGGGAATTGAAGCTGGAGTGACTGCAGCTACTTATACACCTGGTGCATTGCATCCTCACTTGGCCCATTATCACGCACCTCCTCGACTTCATCACTTACAATTAGGAGCTCTTCCTTTAATGGTTCCTGATATGGCAGGCTATCCTCACATCCGTTACATTTCATCAGGATTGGATGGAACATCATTCAGAGGTCCTTTCAGGGGCAATTTTGAGGAACTGATTCATTTGGAAGAAAGATTAGGCAATGTCAATCGTGGAGCATCCCAGGGGACAATTGAAAGATGTACATATCCACATAAATACAAAAAGAGGAAACTGCACTGCAAACAAGATGGGGAAGAAGGGACTGAGGAAGACACAGAGGAAAAATGTACTATCTGTTTGTCTATTTTAGAGGAAGGTGAAGATGTGAGACGTCTTCCATGTATGCACCTTTTCCACCAAGTGTGTGTTGACCAATGGTTGATTACCAATAAGAAGTGCCCCATATGCAGAGTGGACATTGAGGCCCAGCTGCCAAGTGAAAGTTGA