- accession:NM_001130069
- 基因别名:SUMF2
- 基因描述:Homo sapiens sulfatase modifying factor 2 (SUMF2), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:1077
- 翻译后氨基酸长度:358
- TranscriptVariant:This variant (5) lacks the penultimate coding exon, compared to variant 2, resulting in a frameshift and a protein (isoform e) with a longer and distinct C-terminus when compared to isoform b.
- 基因简介:The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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