- accession:NM_001142279
- 基因别名:RNASEH2B
- 基因描述:Homo sapiens ribonuclease H2, subunit B (RNASEH2B), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:774
- 翻译后氨基酸长度:257
- TranscriptVariant:This variant (2) uses an alternate splice pattern in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1.
- 基因简介:RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]
- 规格:10ul 质粒
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