×
![]()
- accession：NM_004228
- 基因别名：CYTH2
- 基因描述：Homo sapiens cytohesin 2 (CYTH2), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1200
- 翻译后氨基酸长度：399
- TranscriptVariant：This variant (2) lacks a 3-nucleotide exon in the PH domain region, compared to variant 1. This results in a protein (isoform 2) missing a single glycine residue, compared to isoform 1.
- 基因简介：The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
