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- accession：NM_001286645
- 基因别名：ADD1
- 基因描述：Homo sapiens adducin 1 (alpha) (ADD1), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：1989
- 翻译后氨基酸长度：662
- TranscriptVariant：This variant (5) differs in the 5' UTR and contains two additional alternate exons compared to variant 1. The resulting isoform (e) has an alternate in-frame segment and a shorter and distinct C-terminus compared to isoform a.
- 基因简介：Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
