- accession:NM_001286683
- 基因别名:AADAT
- 基因描述:Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:1278
- 翻译后氨基酸长度:425
- TranscriptVariant:This variant (4) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b).
- 基因简介:This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
- 规格:10ul 质粒
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