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- accession：NM_020975
- 基因别名：RET
- 基因描述：Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3345
- 翻译后氨基酸长度：1114
- TranscriptVariant：This variant (2) represents the longer transcript and encodes the longer isoform (a). This isoform is also known as Ret51.
- 基因简介：This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
