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- accession：NM_001204863
- 基因别名：TCEB1
- 基因描述：Homo sapiens transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) (TCEB1), transcript variant 8, mRNA.
- 载体：现货载体
- CDS区长度：291
- 翻译后氨基酸长度：96
- TranscriptVariant：This variant (8) lacks an internal exon that results in use of a downstream start codon compared to variant 1. The resulting protein (isoform b) has a shorter N-terminus compared to isoform a. Variants 8 and 9 encode the same protein.
- 基因简介：This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
