- accession:NM_001244810
- 基因别名:FOXP1
- 基因描述:Homo sapiens forkhead box P1 (FOXP1), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:2082
- 翻译后氨基酸长度:693
- TranscriptVariant:This variant (4) lacks an alternate in-frame exon but contains another compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is longer compared to isoform 1. This variant encodes the longest isoform, which has been shown to enhance embryonic stem (ES) cell pluripotency and repress ES cell differentiation.
- 基因简介:This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列