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- accession：NM_001127223
- 基因别名：CD59
- 基因描述：Homo sapiens CD59 molecule, complement regulatory protein (CD59), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：387
- 翻译后氨基酸长度：128
- TranscriptVariant：This variant (5) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.
- 基因简介：This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
