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人 GRP (NM_001012513) cDNA克隆
人 GRP (NM_001012513) cDNA克隆
  • 商品货号:FC109710
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    • accession:NM_001012513
    • 基因别名:GRP
    • 基因描述:Homo sapiens gastrin-releasing peptide (GRP), transcript variant 3, mRNA.
    • 载体:现货载体
    • CDS区长度:417
    • 翻译后氨基酸长度:138
    • TranscriptVariant:This variant (3) uses an alternate splice site in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. It encodes isoform 3 which has a shorter and distinct C-terminus, compared to isoform 1. This variant has also been identified as "splice isoform 2", "pro-gastrin releasing peptide type 3", and "gastrin-releasing peptide nirs variant 1".
    • 基因简介:This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列