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- accession：NM_014043
- 基因别名：CHMP2B
- 基因描述：Homo sapiens charged multivesicular body protein 2B (CHMP2B), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：642
- 翻译后氨基酸长度：213
- TranscriptVariant：This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
- 基因简介：This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
