×
![]()
- accession：NM_001017366
- 基因别名：C4BPB
- 基因描述：Homo sapiens complement component 4 binding protein, beta (C4BPB), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：756
- 翻译后氨基酸长度：251
- TranscriptVariant：This variant (4) differs in the 5' UTR, compared to variant 1, and uses an alternate, in-frame splice site in the 5' coding region. Variants 2 and 4 encode isoform 2, which has a shorter N-terminus, compared to isoform 1.
- 基因简介：This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
