- accession:NM_001034914
- 基因别名:KCNIP3
- 基因描述:Homo sapiens Kv channel interacting protein 3, calsenilin (KCNIP3), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:693
- 翻译后氨基酸长度:230
- TranscriptVariant:This variant (2) includes an alternate in-frame segment in the 5' coding region and uses a downstream start codon, compared to variant 1. The resulting protein (isoform 2) is shorter and has a unique N-terminus, compared to isoform 1.
- 基因简介:This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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