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人 TARDBP (NM_007375) cDNA克隆
人 TARDBP (NM_007375) cDNA克隆
  • 商品货号:FC110756
  • 已售 7 件 | 评价 0 人次 | 关注度 429
    • accession:NM_007375
    • 基因别名:TARDBP
    • 基因描述:Homo sapiens TAR DNA binding protein (TARDBP), mRNA.
    • 载体:现货载体
    • CDS区长度:1245
    • 翻译后氨基酸长度:414
    • 基因简介:HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列